1nci

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[[Image:1nci.gif|left|200px]]<br /><applet load="1nci" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1nci.gif|left|200px]]
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caption="1nci, resolution 2.1&Aring;" />
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'''STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS'''<br />
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{{Structure
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|PDB= 1nci |SIZE=350|CAPTION= <scene name='initialview01'>1nci</scene>, resolution 2.1&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=IUM:URANYL (VI) ION'>IUM</scene>
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|ACTIVITY=
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|GENE=
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}}
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'''STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1NCI is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=IUM:'>IUM</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NCI OCA].
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1NCI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NCI OCA].
==Reference==
==Reference==
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Structural basis of cell-cell adhesion by cadherins., Shapiro L, Fannon AM, Kwong PD, Thompson A, Lehmann MS, Grubel G, Legrand JF, Als-Nielsen J, Colman DR, Hendrickson WA, Nature. 1995 Mar 23;374(6520):327-37. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=7885471 7885471]
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Structural basis of cell-cell adhesion by cadherins., Shapiro L, Fannon AM, Kwong PD, Thompson A, Lehmann MS, Grubel G, Legrand JF, Als-Nielsen J, Colman DR, Hendrickson WA, Nature. 1995 Mar 23;374(6520):327-37. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7885471 7885471]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: cadherin]]
[[Category: cadherin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:04:38 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:55:03 2008''

Revision as of 10:55, 20 March 2008

Image:1nci.gif


PDB ID 1nci

Drag the structure with the mouse to rotate
, resolution 2.1Å
Ligands:
Coordinates: save as pdb, mmCIF, xml



STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS


Overview

Crystal structures of the amino-terminal domain of N-cadherin provide a picture at the atomic level of a specific adhesive contact between cells. A repeated set of dimer interfaces is common to the structure in three lattices. These interactions combine to form a linear zipper of molecules that mirrors the linear structure of the intracellular filaments with which cadherins associate. This cell-adhesion zipper may provide a mechanism to marshal individual molecular adhesive interactions into strong bonds between cells.

About this Structure

1NCI is a Single protein structure of sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

Structural basis of cell-cell adhesion by cadherins., Shapiro L, Fannon AM, Kwong PD, Thompson A, Lehmann MS, Grubel G, Legrand JF, Als-Nielsen J, Colman DR, Hendrickson WA, Nature. 1995 Mar 23;374(6520):327-37. PMID:7885471

Page seeded by OCA on Thu Mar 20 12:55:03 2008

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