1ndn

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[[Image:1ndn.jpg|left|200px]]<br /><applet load="1ndn" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1ndn.jpg|left|200px]]
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caption="1ndn, resolution 3.000&Aring;" />
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'''MOLECULAR STRUCTURE OF NICKED DNA. MODEL T4'''<br />
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{{Structure
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|PDB= 1ndn |SIZE=350|CAPTION= <scene name='initialview01'>1ndn</scene>, resolution 3.000&Aring;
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|SITE=
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|LIGAND=
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|ACTIVITY=
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|GENE=
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}}
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'''MOLECULAR STRUCTURE OF NICKED DNA. MODEL T4'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1NDN is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NDN OCA].
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1NDN is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NDN OCA].
==Reference==
==Reference==
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Molecular structure of nicked DNA: a substrate for DNA repair enzymes., Aymami J, Coll M, van der Marel GA, van Boom JH, Wang AH, Rich A, Proc Natl Acad Sci U S A. 1990 Apr;87(7):2526-30. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=2320572 2320572]
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Molecular structure of nicked DNA: a substrate for DNA repair enzymes., Aymami J, Coll M, van der Marel GA, van Boom JH, Wang AH, Rich A, Proc Natl Acad Sci U S A. 1990 Apr;87(7):2526-30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/2320572 2320572]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Aymani, J.]]
[[Category: Aymani, J.]]
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[[Category: nicked]]
[[Category: nicked]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:05:03 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:55:30 2008''

Revision as of 10:55, 20 March 2008


PDB ID 1ndn

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, resolution 3.000Å
Coordinates: save as pdb, mmCIF, xml



MOLECULAR STRUCTURE OF NICKED DNA. MODEL T4


Overview

The molecular structure of a nicked dodecamer DNA double helix, made of a ternary system containing d(CGCGAAAACGCG) + d(CGCGTT) + d(TTCGCG) oligonucleotides, has been determined by x-ray diffraction analysis at 3 A resolution. The molecule adopts a B-DNA conformation, not unlike those found in intact dodecamer DNA molecules crystallized in a somewhat different crystal lattice, despite a gap due to the absence of a phosphate group in the molecule. The helix has a distinct narrow minor groove near the center of the molecule at the AAAA region. This suggests that the internal stabilizing forces due to base stacking and hydrogen-bonding interactions are sufficient to overcome the loss of connectivity associated with the disruption of the covalent backbone of DNA.

About this Structure

1NDN is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.

Reference

Molecular structure of nicked DNA: a substrate for DNA repair enzymes., Aymami J, Coll M, van der Marel GA, van Boom JH, Wang AH, Rich A, Proc Natl Acad Sci U S A. 1990 Apr;87(7):2526-30. PMID:2320572

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