This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1ntn
From Proteopedia
| Line 1: | Line 1: | ||
| - | [[Image:1ntn.gif|left|200px]] | + | [[Image:1ntn.gif|left|200px]] |
| - | + | ||
| - | '''THE CRYSTAL STRUCTURE OF NEUROTOXIN-I FROM NAJA NAJA OXIANA AT 1.9 ANGSTROMS RESOLUTION''' | + | {{Structure |
| + | |PDB= 1ntn |SIZE=350|CAPTION= <scene name='initialview01'>1ntn</scene>, resolution 1.9Å | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''THE CRYSTAL STRUCTURE OF NEUROTOXIN-I FROM NAJA NAJA OXIANA AT 1.9 ANGSTROMS RESOLUTION''' | ||
| + | |||
==Overview== | ==Overview== | ||
| Line 7: | Line 16: | ||
==About this Structure== | ==About this Structure== | ||
| - | 1NTN is a [ | + | 1NTN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Naja_oxiana Naja oxiana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NTN OCA]. |
==Reference== | ==Reference== | ||
| - | Three-dimensional structure of neurotoxin-1 from Naja naja oxiana venom at 1.9 A resolution., Nickitenko AV, Michailov AM, Betzel C, Wilson KS, FEBS Lett. 1993 Apr 5;320(2):111-7. PMID:[http:// | + | Three-dimensional structure of neurotoxin-1 from Naja naja oxiana venom at 1.9 A resolution., Nickitenko AV, Michailov AM, Betzel C, Wilson KS, FEBS Lett. 1993 Apr 5;320(2):111-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8458425 8458425] |
[[Category: Naja oxiana]] | [[Category: Naja oxiana]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| Line 20: | Line 29: | ||
[[Category: postsynaptic neurotoxin]] | [[Category: postsynaptic neurotoxin]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:01:34 2008'' |
Revision as of 11:01, 20 March 2008
| |||||||
| , resolution 1.9Å | |||||||
|---|---|---|---|---|---|---|---|
| Coordinates: | save as pdb, mmCIF, xml | ||||||
THE CRYSTAL STRUCTURE OF NEUROTOXIN-I FROM NAJA NAJA OXIANA AT 1.9 ANGSTROMS RESOLUTION
Overview
Neurotoxin-1 from Naja naja oxiana venom (NTX-1) has been crystallized by vapor diffusion in sitting drops. The crystals have cell dimensions of a = 25.2 A, b = 75.6 A, c = 35.9 A, and are in space group P2(1)2(1)2(1). Three-dimensional data to 1.9 A have been recorded by a Syntex P2(1) automatic diffractometer. The atomic structure of the toxin has been determined by molecular replacement using the alpha-cobratoxin (alpha-CTX) as the search model. The position of 534 non-hydrogen protein atoms have been determined. The model contains 65 water molecules. Refinement has led to an R-factor of 19.3% at 1.9 A resolution. The secondary and tertiary structures of NTX-1 have been analyzed and a comparison with structure of the alpha-CTX has been made.
About this Structure
1NTN is a Single protein structure of sequence from Naja oxiana. Full crystallographic information is available from OCA.
Reference
Three-dimensional structure of neurotoxin-1 from Naja naja oxiana venom at 1.9 A resolution., Nickitenko AV, Michailov AM, Betzel C, Wilson KS, FEBS Lett. 1993 Apr 5;320(2):111-7. PMID:8458425
Page seeded by OCA on Thu Mar 20 13:01:34 2008
