|
|
Line 1: |
Line 1: |
- | ==Crystal structure of the Thermus thermophilus 70S ribosome in complex with negamycin, mRNA and three deacylated tRNAs in the A, P and E sites==
| + | #REDIRECT [[4w2i]] This PDB entry is obsolete and replaced by 4w2i |
- | <StructureSection load='4rbj' size='340' side='right' caption='[[4rbj]], [[Resolution|resolution]] 2.70Å' scene=''>
| + | |
- | == Structural highlights ==
| + | |
- | <table><tr><td colspan='2'>[[4rbj]] is a 25 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RBJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RBJ FirstGlance]. <br>
| + | |
- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NEG:NEGAMYCIN'>NEG</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
| + | |
- | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=4SU:4-THIOURIDINE-5-MONOPHOSPHATE'>4SU</scene>, <scene name='pdbligand=5MC:5-METHYLCYTIDINE-5-MONOPHOSPHATE'>5MC</scene>, <scene name='pdbligand=5MU:5-METHYLURIDINE+5-MONOPHOSPHATE'>5MU</scene>, <scene name='pdbligand=7MG:7N-METHYL-8-HYDROGUANOSINE-5-MONOPHOSPHATE'>7MG</scene>, <scene name='pdbligand=MIA:2-METHYLTHIO-N6-ISOPENTENYL-ADENOSINE-5-MONOPHOSPHATE'>MIA</scene>, <scene name='pdbligand=PSU:PSEUDOURIDINE-5-MONOPHOSPHATE'>PSU</scene></td></tr>
| + | |
- | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4rbh|4rbh]], [[4rbi|4rbi]], [[4rbk|4rbk]]</td></tr>
| + | |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rbj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rbj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rbj RCSB], [http://www.ebi.ac.uk/pdbsum/4rbj PDBsum]</span></td></tr>
| + | |
- | </table>
| + | |
- | __TOC__
| + | |
- | </StructureSection>
| + | |
- | [[Category: Thermus thermophilus]]
| + | |
- | [[Category: Gupta, P.]]
| + | |
- | [[Category: Jiang, F.]]
| + | |
- | [[Category: Mankin, A S.]]
| + | |
- | [[Category: Matsuda, R.]]
| + | |
- | [[Category: Polikanov, Y S.]]
| + | |
- | [[Category: Shiozuka, M.]]
| + | |
- | [[Category: Steitz, T A.]]
| + | |
- | [[Category: Szal, T.]]
| + | |
- | [[Category: Vazquez-Laslop, Nora]]
| + | |
- | [[Category: 30s subunit with negamycin]]
| + | |
- | [[Category: 50s subunit of the 2nd 70s ribosome in the asu]]
| + | |
- | [[Category: 70s ribosome]]
| + | |
- | [[Category: And e-site trnas of the 2nd 70s ribosome in the asu]]
| + | |
- | [[Category: Antibiotic]]
| + | |
- | [[Category: Deacylated a-]]
| + | |
- | [[Category: Functional complex of bacterial 70s ribosome with antibiotic negamycin]]
| + | |
- | [[Category: Inhibition of translation]]
| + | |
- | [[Category: Miscoding]]
| + | |
- | [[Category: Mrna]]
| + | |
- | [[Category: Negamycin]]
| + | |
- | [[Category: P-]]
| + | |
- | [[Category: Ribosome-antibiotic complex]]
| + | |
- | [[Category: Translocation inhibitor]]
| + | |