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2xd8
From Proteopedia
(Difference between revisions)
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| - | + | ==Capsid structure of the infectious Prochlorococcus Cyanophage P-SSP7== | |
| - | + | <StructureSection load='2xd8' size='340' side='right' caption='[[2xd8]], [[Resolution|resolution]] 4.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| + | <table><tr><td colspan='2'>[[2xd8]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Prochlorococcus_phage_p-ssp7 Prochlorococcus phage p-ssp7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XD8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XD8 FirstGlance]. <br> | ||
| + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xd8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xd8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xd8 RCSB], [http://www.ebi.ac.uk/pdbsum/2xd8 PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xd/2xd8_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Podovirus P-SSP7 infects Prochlorococcus marinus, the most abundant oceanic photosynthetic microorganism. Single-particle cryo-electron microscopy yields icosahedral and asymmetrical structures of infectious P-SSP7 with 4.6-A and 9-A resolution, respectively. The asymmetric reconstruction reveals how symmetry mismatches are accommodated among five of the gene products at the portal vertex. Reconstructions of infectious and empty particles show a conformational change of the 'valve' density in the nozzle, an orientation difference in the tail fibers, a disordering of the C terminus of the portal protein and the disappearance of the core proteins. In addition, cryo-electron tomography of P-SSP7 infecting Prochlorococcus showed the same tail-fiber conformation as that in empty particles. Our observations suggest a mechanism whereby, upon binding to the host cell, the tail fibers induce a cascade of structural alterations of the portal vertex complex that triggers DNA release. | ||
| - | + | Structural changes in a marine podovirus associated with release of its genome into Prochlorococcus.,Liu X, Zhang Q, Murata K, Baker ML, Sullivan MB, Fu C, Dougherty MT, Schmid MF, Osburne MS, Chisholm SW, Chiu W Nat Struct Mol Biol. 2010 Jul;17(7):830-6. Epub 2010 Jun 13. PMID:20543830<ref>PMID:20543830</ref> | |
| - | + | ||
| - | == | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
| - | + | </div> | |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Prochlorococcus phage p-ssp7]] | [[Category: Prochlorococcus phage p-ssp7]] | ||
| - | [[Category: Baker, M L | + | [[Category: Baker, M L]] |
| - | [[Category: Chisholm, S W | + | [[Category: Chisholm, S W]] |
| - | [[Category: Chiu, W | + | [[Category: Chiu, W]] |
| - | [[Category: Dougherty, M | + | [[Category: Dougherty, M]] |
| - | [[Category: Fu, C | + | [[Category: Fu, C]] |
| - | [[Category: Liu, X | + | [[Category: Liu, X]] |
| - | [[Category: Murata, K | + | [[Category: Murata, K]] |
| - | [[Category: Osburne, M S | + | [[Category: Osburne, M S]] |
| - | [[Category: Schmid, M F | + | [[Category: Schmid, M F]] |
| - | [[Category: Sullivan, M B | + | [[Category: Sullivan, M B]] |
| - | [[Category: Zhang, Q | + | [[Category: Zhang, Q]] |
[[Category: Marine podovirus]] | [[Category: Marine podovirus]] | ||
[[Category: T7-like virus]] | [[Category: T7-like virus]] | ||
[[Category: Virus]] | [[Category: Virus]] | ||
Revision as of 11:20, 18 December 2014
Capsid structure of the infectious Prochlorococcus Cyanophage P-SSP7
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