2epp

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{{STRUCTURE_2epp| PDB=2epp | SCENE= }}
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==Solution structure of the first C2H2 type zinc finger domain of Zinc finger protein 278==
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===Solution structure of the first C2H2 type zinc finger domain of Zinc finger protein 278===
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<StructureSection load='2epp' size='340' side='right' caption='[[2epp]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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== Structural highlights ==
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==Disease==
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<table><tr><td colspan='2'>[[2epp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EPP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EPP FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PATZ1, PATZ, RIAZ, ZBTB19, ZNF278, ZSG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2epp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2epp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2epp RCSB], [http://www.ebi.ac.uk/pdbsum/2epp PDBsum], [http://www.topsan.org/Proteins/RSGI/2epp TOPSAN]</span></td></tr>
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</table>
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== Disease ==
[[http://www.uniprot.org/uniprot/PATZ1_HUMAN PATZ1_HUMAN]] Note=A chromosomal aberration involving PATZ1 is associated with small round cell sarcoma. Translocation t(1;22)(p36.1;q12) with EWSR1.
[[http://www.uniprot.org/uniprot/PATZ1_HUMAN PATZ1_HUMAN]] Note=A chromosomal aberration involving PATZ1 is associated with small round cell sarcoma. Translocation t(1;22)(p36.1;q12) with EWSR1.
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== Function ==
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==Function==
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[[http://www.uniprot.org/uniprot/PATZ1_HUMAN PATZ1_HUMAN]] Transcriptional repressor.<ref>PMID:10713105</ref>
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[[http://www.uniprot.org/uniprot/PATZ1_HUMAN PATZ1_HUMAN]] Transcriptional repressor.<ref>PMID:10713105</ref>
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==About this Structure==
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[[2epp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EPP OCA].
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==See Also==
==See Also==
*[[Zinc Fingers|Zinc Fingers]]
*[[Zinc Fingers|Zinc Fingers]]
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== References ==
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==Reference==
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<references/>
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<references group="xtra"/><references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Inoue, M.]]
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[[Category: Inoue, M]]
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[[Category: Kigawa, T.]]
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[[Category: Kigawa, T]]
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[[Category: Muto, Y.]]
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[[Category: Muto, Y]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Structural genomic]]
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[[Category: Shirouzu, M.]]
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[[Category: Shirouzu, M]]
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[[Category: Suzuki, S.]]
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[[Category: Suzuki, S]]
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[[Category: Tanabe, W.]]
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[[Category: Tanabe, W]]
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[[Category: Terada, T.]]
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[[Category: Terada, T]]
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[[Category: Yokoyama, S.]]
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[[Category: Yokoyama, S]]
[[Category: C2h2]]
[[Category: C2h2]]
[[Category: National project on protein structural and functional analyse]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Nppsfa]]
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[[Category: Riken structural genomics/proteomics initiative]]
 
[[Category: Rsgi]]
[[Category: Rsgi]]
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[[Category: Structural genomic]]
 
[[Category: Transcription]]
[[Category: Transcription]]
[[Category: Zinc finger domain]]
[[Category: Zinc finger domain]]

Revision as of 11:50, 18 December 2014

Solution structure of the first C2H2 type zinc finger domain of Zinc finger protein 278

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