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3psn

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{{STRUCTURE_3psn| PDB=3psn | SCENE= }}
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==Crystal structure of mouse VPS29 complexed with Mn2+==
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===Crystal structure of mouse VPS29 complexed with Mn2+===
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<StructureSection load='3psn' size='340' side='right' caption='[[3psn]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[3psn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3lh7 3lh7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PSN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PSN FirstGlance]. <br>
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[[http://www.uniprot.org/uniprot/VPS29_MOUSE VPS29_MOUSE]] Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro).
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1w24|1w24]], [[1x2x|1x2x]], [[1z2w|1z2w]], [[2a22|2a22]], [[2r17|2r17]], [[3pso|3pso]]</td></tr>
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==About this Structure==
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Vps29 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
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[[3psn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3lh7 3lh7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PSN OCA].
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoserine_phosphatase Phosphoserine phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.3 3.1.3.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3psn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3psn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3psn RCSB], [http://www.ebi.ac.uk/pdbsum/3psn PDBsum]</span></td></tr>
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</table>
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__TOC__
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</StructureSection>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Phosphoserine phosphatase]]
[[Category: Phosphoserine phosphatase]]
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[[Category: Chhabra, S.]]
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[[Category: Chhabra, S]]
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[[Category: Collins, B.]]
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[[Category: Collins, B]]
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[[Category: Ghai, R.]]
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[[Category: Ghai, R]]
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[[Category: Norwood, S.]]
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[[Category: Norwood, S]]
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[[Category: Shaw, D.]]
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[[Category: Shaw, D]]
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[[Category: Swarbrick, J.]]
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[[Category: Swarbrick, J]]
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[[Category: Valkov, E.]]
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[[Category: Valkov, E]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Membrane trafficking]]
[[Category: Membrane trafficking]]

Revision as of 11:08, 19 December 2014

Crystal structure of mouse VPS29 complexed with Mn2+

3psn, resolution 2.40Å

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