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1rii

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[[Image:1rii.gif|left|200px]]<br /><applet load="1rii" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1rii.gif|left|200px]]
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caption="1rii, resolution 1.70&Aring;" />
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'''Crystal structure of phosphoglycerate mutase from M. Tuberculosis'''<br />
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{{Structure
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|PDB= 1rii |SIZE=350|CAPTION= <scene name='initialview01'>1rii</scene>, resolution 1.70&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Phosphoglycerate_mutase Phosphoglycerate mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.2.1 5.4.2.1]
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|GENE= GPMA, GPM, PGM, GPM1, RV0489, MT0508, MTCY20G9.15, MB0499 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])
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}}
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'''Crystal structure of phosphoglycerate mutase from M. Tuberculosis'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1RII is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis] with <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Phosphoglycerate_mutase Phosphoglycerate mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.2.1 5.4.2.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RII OCA].
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1RII is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RII OCA].
==Reference==
==Reference==
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The 1.70 angstroms X-ray crystal structure of Mycobacterium tuberculosis phosphoglycerate mutase., Muller P, Sawaya MR, Pashkov I, Chan S, Nguyen C, Wu Y, Perry LJ, Eisenberg D, Acta Crystallogr D Biol Crystallogr. 2005 Mar;61(Pt 3):309-15. Epub 2005, Feb 24. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15735341 15735341]
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The 1.70 angstroms X-ray crystal structure of Mycobacterium tuberculosis phosphoglycerate mutase., Muller P, Sawaya MR, Pashkov I, Chan S, Nguyen C, Wu Y, Perry LJ, Eisenberg D, Acta Crystallogr D Biol Crystallogr. 2005 Mar;61(Pt 3):309-15. Epub 2005, Feb 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15735341 15735341]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Phosphoglycerate mutase]]
[[Category: Phosphoglycerate mutase]]
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[[Category: psi]]
[[Category: psi]]
[[Category: sh3 domain binding]]
[[Category: sh3 domain binding]]
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[[Category: structural genomics]]
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[[Category: structural genomic]]
[[Category: tb structural genomics consortium]]
[[Category: tb structural genomics consortium]]
[[Category: tbsgc]]
[[Category: tbsgc]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:51:15 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:52:04 2008''

Revision as of 11:52, 20 March 2008

Image:1rii.gif


PDB ID 1rii

Drag the structure with the mouse to rotate
, resolution 1.70Å
Ligands:
Gene: GPMA, GPM, PGM, GPM1, RV0489, MT0508, MTCY20G9.15, MB0499 (Mycobacterium tuberculosis)
Activity: Phosphoglycerate mutase, with EC number 5.4.2.1
Coordinates: save as pdb, mmCIF, xml



Crystal structure of phosphoglycerate mutase from M. Tuberculosis


Overview

The single-crystal X-ray structure of phosphoglycerate mutase from Mycobacterium tuberculosis has been determined at a resolution of 1.70 angstroms. The C-terminal tail of each of the subunits is flexible and disordered; however, for one of the four chains (chain A) all but five residues of the chain could be modeled. Noteworthy features of the structure include the active site and a proline-rich segment in each monomer forming a short left-handed polyprolyl helix. These segments lie on the enzyme surface and could conceivably participate in protein-protein interactions.

About this Structure

1RII is a Single protein structure of sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

The 1.70 angstroms X-ray crystal structure of Mycobacterium tuberculosis phosphoglycerate mutase., Muller P, Sawaya MR, Pashkov I, Chan S, Nguyen C, Wu Y, Perry LJ, Eisenberg D, Acta Crystallogr D Biol Crystallogr. 2005 Mar;61(Pt 3):309-15. Epub 2005, Feb 24. PMID:15735341

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