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4b43

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{{STRUCTURE_4b43| PDB=4b43 | SCENE= }}
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==Bacterial translation initiation factor IF2 (1-363), apo form, double mutant K86L H130A==
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===Bacterial translation initiation factor IF2 (1-363), apo form, double mutant K86L H130A===
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<StructureSection load='4b43' size='340' side='right' caption='[[4b43]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[4b43]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B43 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B43 FirstGlance]. <br>
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[[http://www.uniprot.org/uniprot/IF2_THET8 IF2_THET8]] One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity).
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4b3x|4b3x]], [[4b44|4b44]], [[4b47|4b47]], [[4b48|4b48]]</td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b43 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b43 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4b43 RCSB], [http://www.ebi.ac.uk/pdbsum/4b43 PDBsum]</span></td></tr>
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[[4b43]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B43 OCA].
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</table>
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__TOC__
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</StructureSection>
[[Category: Thermus thermophilus hb8]]
[[Category: Thermus thermophilus hb8]]
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[[Category: Klaholz, B P.]]
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[[Category: Klaholz, B P]]
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[[Category: Simonetti, A.]]
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[[Category: Simonetti, A]]
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[[Category: Urzhumtsev, A.]]
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[[Category: Urzhumtsev, A]]
[[Category: Gtp hydrolysis mechanism]]
[[Category: Gtp hydrolysis mechanism]]
[[Category: Initiation]]
[[Category: Initiation]]
[[Category: Translation]]
[[Category: Translation]]

Revision as of 09:45, 21 December 2014

Bacterial translation initiation factor IF2 (1-363), apo form, double mutant K86L H130A

4b43, resolution 1.94Å

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