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1rw1

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[[Image:1rw1.gif|left|200px]]<br /><applet load="1rw1" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1rw1.gif|left|200px]]
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caption="1rw1, resolution 1.02&Aring;" />
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'''YFFB (PA3664) PROTEIN'''<br />
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{{Structure
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|PDB= 1rw1 |SIZE=350|CAPTION= <scene name='initialview01'>1rw1</scene>, resolution 1.02&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=IPA:ISOPROPYL ALCOHOL'>IPA</scene>
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|ACTIVITY=
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|GENE= yffB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 Pseudomonas aeruginosa PAO1])
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}}
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'''YFFB (PA3664) PROTEIN'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1RW1 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1] with <scene name='pdbligand=IPA:'>IPA</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RW1 OCA].
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1RW1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RW1 OCA].
==Reference==
==Reference==
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Crystal structure of the YffB protein from Pseudomonas aeruginosa suggests a glutathione-dependent thiol reductase function., Teplyakov A, Pullalarevu S, Obmolova G, Doseeva V, Galkin A, Herzberg O, Dauter M, Dauter Z, Gilliland GL, BMC Struct Biol. 2004 Mar 8;4:5. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15102337 15102337]
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Crystal structure of the YffB protein from Pseudomonas aeruginosa suggests a glutathione-dependent thiol reductase function., Teplyakov A, Pullalarevu S, Obmolova G, Doseeva V, Galkin A, Herzberg O, Dauter M, Dauter Z, Gilliland GL, BMC Struct Biol. 2004 Mar 8;4:5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15102337 15102337]
[[Category: Pseudomonas aeruginosa pao1]]
[[Category: Pseudomonas aeruginosa pao1]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: IPA]]
[[Category: IPA]]
[[Category: s2f]]
[[Category: s2f]]
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[[Category: structural genomics]]
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[[Category: structural genomic]]
[[Category: structure 2 function project]]
[[Category: structure 2 function project]]
[[Category: thioredoxin fold]]
[[Category: thioredoxin fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:55:06 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:56:57 2008''

Revision as of 11:57, 20 March 2008

Image:1rw1.gif


PDB ID 1rw1

Drag the structure with the mouse to rotate
, resolution 1.02Å
Ligands:
Gene: yffB (Pseudomonas aeruginosa PAO1)
Coordinates: save as pdb, mmCIF, xml



YFFB (PA3664) PROTEIN


Overview

BACKGROUND: The yffB (PA3664) gene of Pseudomonas aeruginosa encodes an uncharacterized protein of 13 kDa molecular weight with a marginal sequence similarity to arsenate reductase from Escherichia coli. The crystal structure determination of YffB was undertaken as part of a structural genomics effort in order to assist with the functional assignment of the protein. RESULTS: The structure was determined at 1.0 A resolution by single-wavelength anomalous diffraction. The fold is very similar to that of arsenate reductase, which is an extension of the thioredoxin fold. CONCLUSION: Given the conservation of the functionally important residues and the ability to bind glutathione, YffB is likely to function as a GSH-dependent thiol reductase.

About this Structure

1RW1 is a Single protein structure of sequence from Pseudomonas aeruginosa pao1. Full crystallographic information is available from OCA.

Reference

Crystal structure of the YffB protein from Pseudomonas aeruginosa suggests a glutathione-dependent thiol reductase function., Teplyakov A, Pullalarevu S, Obmolova G, Doseeva V, Galkin A, Herzberg O, Dauter M, Dauter Z, Gilliland GL, BMC Struct Biol. 2004 Mar 8;4:5. PMID:15102337

Page seeded by OCA on Thu Mar 20 13:56:57 2008

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