This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4mqb

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
{{STRUCTURE_4mqb| PDB=4mqb | SCENE= }}
+
==Crystal structure of thymidylate kinase from Staphylococcus aureus in complex with 2-(N-morpholino)ethanesulfonic acid==
-
===Crystal structure of thymidylate kinase from Staphylococcus aureus in complex with 2-(N-morpholino)ethanesulfonic acid===
+
<StructureSection load='4mqb' size='340' side='right' caption='[[4mqb]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[4mqb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_mu50 Staphylococcus aureus subsp. aureus mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MQB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MQB FirstGlance]. <br>
 +
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
 +
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
 +
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4eaq|4eaq]], [[4f4i|4f4i]], [[4dwj|4dwj]]</td></tr>
 +
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tmk, SAV0482 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158878 Staphylococcus aureus subsp. aureus Mu50])</td></tr>
 +
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9] </span></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mqb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mqb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mqb RCSB], [http://www.ebi.ac.uk/pdbsum/4mqb PDBsum]</span></td></tr>
 +
</table>
-
==Function==
+
==See Also==
-
[[http://www.uniprot.org/uniprot/KTHY_STAAM KTHY_STAAM]] Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity).
+
*[[Thymidylate kinase|Thymidylate kinase]]
-
 
+
__TOC__
-
==About this Structure==
+
</StructureSection>
-
[[4mqb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_mu50 Staphylococcus aureus subsp. aureus mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MQB OCA].
+
[[Category: Staphylococcus aureus subsp. aureus mu50]]
[[Category: Staphylococcus aureus subsp. aureus mu50]]
[[Category: DTMP kinase]]
[[Category: DTMP kinase]]
-
[[Category: Anderson, W F.]]
+
[[Category: Anderson, W F]]
-
[[Category: Babnigg, G.]]
+
[[Category: Babnigg, G]]
-
[[Category: Filippova, E V.]]
+
[[Category: Filippova, E V]]
-
[[Category: Jedrzejczak, R.]]
+
[[Category: Jedrzejczak, R]]
-
[[Category: Joachimiak, A.]]
+
[[Category: Joachimiak, A]]
-
[[Category: Kiryukhina, O.]]
+
[[Category: Kiryukhina, O]]
-
[[Category: MCSG, Midwest Center for Structural Genomics.]]
+
[[Category: Structural genomic]]
-
[[Category: MTBI, Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors.]]
+
[[Category: MTBI, Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors]]
-
[[Category: Minasov, G.]]
+
[[Category: Minasov, G]]
-
[[Category: Rubin, E.]]
+
[[Category: Rubin, E]]
-
[[Category: Sacchettini, J.]]
+
[[Category: Sacchettini, J]]
-
[[Category: Shuvalova, L.]]
+
[[Category: Shuvalova, L]]
[[Category: Mcsg]]
[[Category: Mcsg]]
-
[[Category: Midwest center for structural genomic]]
 
[[Category: Mtb proteins conferring susceptibility to known mtb inhibitor]]
[[Category: Mtb proteins conferring susceptibility to known mtb inhibitor]]
[[Category: Mtbi]]
[[Category: Mtbi]]
[[Category: Psi-biology]]
[[Category: Psi-biology]]
-
[[Category: Structural genomic]]
 
[[Category: Thymidylate kinase]]
[[Category: Thymidylate kinase]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 15:09, 21 December 2014

Crystal structure of thymidylate kinase from Staphylococcus aureus in complex with 2-(N-morpholino)ethanesulfonic acid

4mqb, resolution 1.55Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools