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4l1r

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{{STRUCTURE_4l1r| PDB=4l1r | SCENE= }}
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==Glycoprotein B from Herpes Simplex Virus type 1, A549T Rate-of-Entry mutant, low-pH==
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===Glycoprotein B from Herpes Simplex Virus type 1, A549T Rate-of-Entry mutant, low-pH===
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<StructureSection load='4l1r' size='340' side='right' caption='[[4l1r]], [[Resolution|resolution]] 3.03&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4l1r]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_herpesvirus_1_strain_kos Human herpesvirus 1 strain kos]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L1R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4L1R FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2gum|2gum]], [[3nwf|3nwf]], [[3nwa|3nwa]], [[3nwd|3nwd]], [[3nw8|3nw8]], [[4hsi|4hsi]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gB, UL27 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10306 Human herpesvirus 1 strain KOS])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l1r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l1r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4l1r RCSB], [http://www.ebi.ac.uk/pdbsum/4l1r PDBsum]</span></td></tr>
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</table>
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==Function==
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==See Also==
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[[http://www.uniprot.org/uniprot/GB_HHV1K GB_HHV1K]] Envelope glycoprotein that forms spikes at the surface of virion envelope. Essential for the initial attachment to heparan sulfate moities of the host cell surface proteoglycans. Involved in fusion of viral and cellular membranes leading to virus entry into the host cell. Following initial binding of gD to one of its receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress. Also plays a role, together with gK, in virus-induced cell-to-cell fusion (syncytia formation).<ref>PMID:17299053</ref>
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*[[Glycoproteins B and D|Glycoproteins B and D]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[4l1r]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_herpesvirus_1_strain_kos Human herpesvirus 1 strain kos]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L1R OCA].
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==Reference==
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<references group="xtra"/><references/>
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[[Category: Human herpesvirus 1 strain kos]]
[[Category: Human herpesvirus 1 strain kos]]
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[[Category: Heldwein, E E.]]
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[[Category: Heldwein, E E]]
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[[Category: Stampfer, S D.]]
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[[Category: Stampfer, S D]]
[[Category: Coiled-coil]]
[[Category: Coiled-coil]]
[[Category: Entry rate]]
[[Category: Entry rate]]

Revision as of 15:12, 21 December 2014

Glycoprotein B from Herpes Simplex Virus type 1, A549T Rate-of-Entry mutant, low-pH

4l1r, resolution 3.03Å

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