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4lhr

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{{STRUCTURE_4lhr| PDB=4lhr | SCENE= }}
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==Crystal structure of a deoxyuridine 5'-triphosphate nucleotidohydrolase from Burkholderia thailandensis==
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===Crystal structure of a deoxyuridine 5'-triphosphate nucleotidohydrolase from Burkholderia thailandensis===
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<StructureSection load='4lhr' size='340' side='right' caption='[[4lhr]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4lhr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Burkholderia_thailandensis_e264 Burkholderia thailandensis e264]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LHR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LHR FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BTH_I0767, dut ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=271848 Burkholderia thailandensis E264])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dUTP_diphosphatase dUTP diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.23 3.6.1.23] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lhr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lhr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lhr RCSB], [http://www.ebi.ac.uk/pdbsum/4lhr PDBsum]</span></td></tr>
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</table>
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==Function==
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==See Also==
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[[http://www.uniprot.org/uniprot/DUT_BURTA DUT_BURTA]] This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity).
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*[[Deoxyuridine 5'-triphosphate nucleotidohydrolase|Deoxyuridine 5'-triphosphate nucleotidohydrolase]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[4lhr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Burkholderia_thailandensis_e264 Burkholderia thailandensis e264]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LHR OCA].
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[[Category: Burkholderia thailandensis e264]]
[[Category: Burkholderia thailandensis e264]]
[[Category: DUTP diphosphatase]]
[[Category: DUTP diphosphatase]]
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[[Category: SSGCID, Seattle Structural Genomics Center for Infectious Disease.]]
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[[Category: Structural genomic]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: National institute of allergy and infectious disease]]
[[Category: National institute of allergy and infectious disease]]
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[[Category: Nucleotide metabolism]]
[[Category: Nucleotide metabolism]]
[[Category: Pyrimidine]]
[[Category: Pyrimidine]]
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[[Category: Seattle structural genomics center for infectious disease]]
 
[[Category: Ssgcid]]
[[Category: Ssgcid]]
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[[Category: Structural genomic]]
 

Revision as of 15:38, 21 December 2014

Crystal structure of a deoxyuridine 5'-triphosphate nucleotidohydrolase from Burkholderia thailandensis

4lhr, resolution 1.50Å

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