This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3ai8

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
{{STRUCTURE_3ai8| PDB=3ai8 | SCENE= }}
+
==Cathepsin B in complex with the nitroxoline==
-
===Cathepsin B in complex with the nitroxoline===
+
<StructureSection load='3ai8' size='340' side='right' caption='[[3ai8]], [[Resolution|resolution]] 2.11&Aring;' scene=''>
-
 
+
== Structural highlights ==
-
==Function==
+
<table><tr><td colspan='2'>[[3ai8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AI8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AI8 FirstGlance]. <br>
-
[[http://www.uniprot.org/uniprot/CATB_HUMAN CATB_HUMAN]] Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HNQ:5-NITROQUINOLIN-8-OL'>HNQ</scene></td></tr>
-
 
+
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CTSB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-
==About this Structure==
+
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_B Cathepsin B], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.1 3.4.22.1] </span></td></tr>
-
[[3ai8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AI8 OCA].
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ai8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ai8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ai8 RCSB], [http://www.ebi.ac.uk/pdbsum/3ai8 PDBsum]</span></td></tr>
 +
</table>
==See Also==
==See Also==
*[[Cathepsin|Cathepsin]]
*[[Cathepsin|Cathepsin]]
-
 
+
__TOC__
-
==Reference==
+
</StructureSection>
-
<ref group="xtra">PMID:021598397</ref><references group="xtra"/><references/>
+
[[Category: Cathepsin B]]
[[Category: Cathepsin B]]
[[Category: Human]]
[[Category: Human]]
-
[[Category: Gobec, S.]]
+
[[Category: Gobec, S]]
-
[[Category: Kos, J.]]
+
[[Category: Kos, J]]
-
[[Category: Mirkovic, B.]]
+
[[Category: Mirkovic, B]]
-
[[Category: Renko, M.]]
+
[[Category: Renko, M]]
-
[[Category: Turk, D.]]
+
[[Category: Turk, D]]
[[Category: 8-hydroxy-5-nitroquinoline]]
[[Category: 8-hydroxy-5-nitroquinoline]]
[[Category: Cathepsin b]]
[[Category: Cathepsin b]]

Revision as of 18:03, 21 December 2014

Cathepsin B in complex with the nitroxoline

3ai8, resolution 2.11Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools