This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2miu

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
{{STRUCTURE_2miu| PDB=2miu | SCENE= }}
+
==Structure of FHL2 LIM adaptor and its Interaction with Ski==
-
===Structure of FHL2 LIM adaptor and its Interaction with Ski===
+
<StructureSection load='2miu' size='340' side='right' caption='[[2miu]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
-
 
+
== Structural highlights ==
-
==Function==
+
<table><tr><td colspan='2'>[[2miu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MIU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MIU FirstGlance]. <br>
-
[[http://www.uniprot.org/uniprot/FHL2_HUMAN FHL2_HUMAN]] May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation.<ref>PMID:15692560</ref> <ref>PMID:16652157</ref> <ref>PMID:18853468</ref>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
 
+
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FHL2, DRAL, SLIM3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2miu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2miu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2miu RCSB], [http://www.ebi.ac.uk/pdbsum/2miu PDBsum]</span></td></tr>
-
[[2miu]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MIU OCA].
+
</table>
-
 
+
__TOC__
-
==Reference==
+
</StructureSection>
-
<references group="xtra"/><references/>
+
[[Category: Human]]
-
[[Category: Medrano, E E.]]
+
[[Category: Medrano, E E]]
-
[[Category: Sun, Y.]]
+
[[Category: Sun, Y]]
-
[[Category: Tian, X.]]
+
[[Category: Tian, X]]
-
[[Category: Weiss, M A.]]
+
[[Category: Weiss, M A]]
-
[[Category: Yang, Y.]]
+
[[Category: Yang, Y]]
[[Category: Fhl2]]
[[Category: Fhl2]]
[[Category: Lim domain]]
[[Category: Lim domain]]
[[Category: Protein binding]]
[[Category: Protein binding]]

Revision as of 18:38, 21 December 2014

Structure of FHL2 LIM adaptor and its Interaction with Ski

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools