1tag

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1tag.gif|left|200px]]<br /><applet load="1tag" size="350" color="white" frame="true" align="right" spinBox="true"
+
[[Image:1tag.gif|left|200px]]
-
caption="1tag, resolution 1.8&Aring;" />
+
 
-
'''STRUCTURAL DETERMINANTS FOR ACTIVATION OF THE ALPHA-SUBUNIT OF A HETEROTRIMERIC G PROTEIN'''<br />
+
{{Structure
 +
|PDB= 1tag |SIZE=350|CAPTION= <scene name='initialview01'>1tag</scene>, resolution 1.8&Aring;
 +
|SITE=
 +
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=GDP:GUANOSINE-5'-DIPHOSPHATE'>GDP</scene>
 +
|ACTIVITY=
 +
|GENE=
 +
}}
 +
 
 +
'''STRUCTURAL DETERMINANTS FOR ACTIVATION OF THE ALPHA-SUBUNIT OF A HETEROTRIMERIC G PROTEIN'''
 +
 
==Overview==
==Overview==
Line 7: Line 16:
==About this Structure==
==About this Structure==
-
1TAG is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=GDP:'>GDP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TAG OCA].
+
1TAG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TAG OCA].
==Reference==
==Reference==
-
Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein., Lambright DG, Noel JP, Hamm HE, Sigler PB, Nature. 1994 Jun 23;369(6482):621-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8208289 8208289]
+
Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein., Lambright DG, Noel JP, Hamm HE, Sigler PB, Nature. 1994 Jun 23;369(6482):621-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8208289 8208289]
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Single protein]]
[[Category: Single protein]]
Line 21: Line 30:
[[Category: gtp-binding protein]]
[[Category: gtp-binding protein]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:11:34 2008''
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:15:58 2008''

Revision as of 12:15, 20 March 2008

Image:1tag.gif


PDB ID 1tag

Drag the structure with the mouse to rotate
, resolution 1.8Å
Ligands: and
Coordinates: save as pdb, mmCIF, xml



STRUCTURAL DETERMINANTS FOR ACTIVATION OF THE ALPHA-SUBUNIT OF A HETEROTRIMERIC G PROTEIN


Overview

The 1.8 A crystal structure of transducin alpha.GDP, when compared to that of the activated complex with GTP-gamma S, reveals the nature of the conformational changes that occur on activation of a heterotrimeric G-protein alpha-subunit. Structural changes initiated by direct contacts with the terminal phosphate of GTP propagate to regions that have been implicated in effector activation. The changes are distinct from those observed in other members of the GTPase superfamily.

About this Structure

1TAG is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein., Lambright DG, Noel JP, Hamm HE, Sigler PB, Nature. 1994 Jun 23;369(6482):621-8. PMID:8208289

Page seeded by OCA on Thu Mar 20 14:15:58 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1tag"
Personal tools