1a5v

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1a5v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rous_sarcoma_virus_(strain_schmidt-ruppin) Rous sarcoma virus (strain schmidt-ruppin)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A5V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A5V FirstGlance]. <br>
<table><tr><td colspan='2'>[[1a5v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rous_sarcoma_virus_(strain_schmidt-ruppin) Rous sarcoma virus (strain schmidt-ruppin)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A5V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1A5V FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=Y3:4-ACETYLAMINO-5-HYDROXYNAPHTHALENE-2,7-DISULFONIC+ACID'>Y3</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=Y3:4-ACETYLAMINO-5-HYDROXYNAPHTHALENE-2,7-DISULFONIC+ACID'>Y3</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a5v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a5v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1a5v RCSB], [http://www.ebi.ac.uk/pdbsum/1a5v PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a5v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a5v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1a5v RCSB], [http://www.ebi.ac.uk/pdbsum/1a5v PDBsum]</span></td></tr>
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<table>
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</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: RNA-directed DNA polymerase]]
[[Category: RNA-directed DNA polymerase]]
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[[Category: Alexandratos, J.]]
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[[Category: Alexandratos, J]]
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[[Category: Lubkowski, J.]]
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[[Category: Lubkowski, J]]
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[[Category: Wlodawer, A.]]
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[[Category: Wlodawer, A]]
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[[Category: Yang, F.]]
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[[Category: Yang, F]]
[[Category: Endonuclease]]
[[Category: Endonuclease]]
[[Category: Hiv-1 integrase inhibitor]]
[[Category: Hiv-1 integrase inhibitor]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]

Revision as of 10:17, 22 December 2014

ASV INTEGRASE CORE DOMAIN WITH HIV-1 INTEGRASE INHIBITOR Y3 AND MN CATION

1a5v, resolution 1.90Å

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