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User:Nicholas P. Taliceo/Sandbox
From Proteopedia
< User:Nicholas P. Taliceo(Difference between revisions)
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| - | + | <StructureSection load='1eqg' size='340' side='right' caption='Caption for this structure' scene='60/609967/Ibuprofen_single_molecule/5'> | |
| - | <StructureSection load='1eqg' size='340' side='right' caption='Caption for this structure' scene=' | + | |
| - | + | ||
| - | + | ||
| - | + | '''Structure of the Ibuprofen Molecule''' | |
| - | <jmol> | + | <scene name='60/609967/Ibuprofen_single_molecule/5'>Ibuprofen Single Molecule</scene> |
| + | |||
| + | *<jmol> | ||
| + | <jmolLink> | ||
| + | <script> select 701:A; color CPK; spacefill 23%; var a = [300,250,200,170,140,120,100]; for(var i IN a) {wireframe @i; delay 0.4;} | ||
| + | </script> | ||
| + | <text>Show the atoms </text> | ||
| + | </jmolLink> | ||
| + | </jmol> | ||
| + | |||
| + | |||
| + | |||
| + | '''Ibuprofen binds to the protein cyclooxygenase''' | ||
| + | |||
| + | |||
| + | <scene name='60/609967/Allatom/4'>Protein buries ligands</scene> | ||
| + | |||
| + | *<jmol> | ||
<jmolLink> | <jmolLink> | ||
<script> slab on; depth 40; var a = [90,80,70,60,55,54,53,52,51]; for(var i IN a) {slab @i; delay 0.4;} | <script> slab on; depth 40; var a = [90,80,70,60,55,54,53,52,51]; for(var i IN a) {slab @i; delay 0.4;} | ||
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</jmol> | </jmol> | ||
| - | <jmol> | + | *<jmol> |
<jmolLink> | <jmolLink> | ||
| - | <script> slab on; depth 40; var a = [51,52,53,54,55,60,70,80,90]; for(var i IN a) {slab @i; delay 0.4;} | + | <script> slab on; depth 40; var a = [51,52,53,54,55,60,70,80,90,100]; for(var i IN a) {slab @i; delay 0.4;} |
</script> | </script> | ||
<text>Slab out of center</text> | <text>Slab out of center</text> | ||
| Line 22: | Line 36: | ||
</jmol> | </jmol> | ||
| - | == Function == | ||
| - | == Disease == | ||
| - | <scene name='60/609967/Ibuprofen_only/1'>Ibuprofen Molecules</scene> | ||
| - | |||
| - | <scene name='60/609967/Ibuprofen_single_molecule/5'>Ibuprofen Single Molecule</scene> | ||
| - | <scene name='60/609967/Ibuprofen_single_molecule/4'>Ibuprofen Single Molecule</scene> | ||
| - | == Relevance == | ||
| - | |||
| - | == Structural highlights == | ||
| - | |||
| - | This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | ||
</StructureSection> | </StructureSection> | ||
| - | == | + | == Function == |
| - | < | + | The protein sits on the surface of a membrane, and makes prostaglandin hormones when not inhibited. There is a nice [http://www.rcsb.org/pdb/education_discussion/molecule_of_the_month/images/4cox_tunnel.gif figure] of the protein and the membrane in a molecule of the month article by David Goodsell. |
| + | |||
| + | <scene name='60/609967/With_membrane/1'>Membrane orientation</scene> | ||
Current revision
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Function
The protein sits on the surface of a membrane, and makes prostaglandin hormones when not inhibited. There is a nice figure of the protein and the membrane in a molecule of the month article by David Goodsell.
