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2esb
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2esb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ESB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ESB FirstGlance]. <br> | <table><tr><td colspan='2'>[[2esb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ESB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ESB FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2esb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2esb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2esb RCSB], [http://www.ebi.ac.uk/pdbsum/2esb PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2esb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2esb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2esb RCSB], [http://www.ebi.ac.uk/pdbsum/2esb PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DUS18_HUMAN DUS18_HUMAN]] Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine. In vitro, dephosphorylates p-nitrophenyl phosphate (pNPP). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Cho, Y H | + | [[Category: Cho, Y H]] |
| - | [[Category: Jeong, D G | + | [[Category: Jeong, D G]] |
| - | [[Category: Kim, J H | + | [[Category: Kim, J H]] |
| - | [[Category: Kim, S J | + | [[Category: Kim, S J]] |
| - | [[Category: Ryu, S E | + | [[Category: Ryu, S E]] |
| - | [[Category: Yoon, T S | + | [[Category: Yoon, T S]] |
[[Category: Alpha/beta structure]] | [[Category: Alpha/beta structure]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
Revision as of 07:01, 24 December 2014
Crystal structure of human DUSP18
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Categories: Homo sapiens | Cho, Y H | Jeong, D G | Kim, J H | Kim, S J | Ryu, S E | Yoon, T S | Alpha/beta structure | Hydrolase
