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3era
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3era FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3era OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3era RCSB], [http://www.ebi.ac.uk/pdbsum/3era PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3era FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3era OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3era RCSB], [http://www.ebi.ac.uk/pdbsum/3era PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NXSA_LATSE NXSA_LATSE]] Binds with high affinity to muscular nicotinic acetylcholine receptors (nAChRs), and with low affinity to neuronal alpha-7 nAChRs. Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site. Blocks the extracellular increase of dopamine evoked by nicotine at 4.2 uM concentrations.<ref>PMID:9305882</ref> <ref>PMID:9840221</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 07:15, 24 December 2014
RECOMBINANT ERABUTOXIN A (S8T MUTANT)
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