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2krr
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2krr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2krr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2krr RCSB], [http://www.ebi.ac.uk/pdbsum/2krr PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2krr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2krr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2krr RCSB], [http://www.ebi.ac.uk/pdbsum/2krr PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NUCL_HUMAN NUCL_HUMAN]] Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats.<ref>PMID:10393184</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Arumugam, N | + | [[Category: Arumugam, N]] |
| - | [[Category: Bates, P J | + | [[Category: Bates, P J]] |
| - | [[Category: Lane, A N | + | [[Category: Lane, A N]] |
| - | [[Category: Maliekal, J | + | [[Category: Maliekal, J]] |
| - | [[Category: Miller, C | + | [[Category: Miller, C]] |
| - | [[Category: Trent, J O | + | [[Category: Trent, J O]] |
[[Category: Dna-binding]] | [[Category: Dna-binding]] | ||
[[Category: Methylation]] | [[Category: Methylation]] | ||
Revision as of 07:28, 24 December 2014
Solution structure of the RBD1,2 domains from human nucleolin
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Categories: Homo sapiens | Arumugam, N | Bates, P J | Lane, A N | Maliekal, J | Miller, C | Trent, J O | Dna-binding | Methylation | Nuclear protein | Nucleus | Phosphoprotein | Rna-binding
