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2biv

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2biv]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BIV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BIV FirstGlance]. <br>
<table><tr><td colspan='2'>[[2biv]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BIV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BIV FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1oi1|1oi1]], [[2vyt|2vyt]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1oi1|1oi1]], [[2vyt|2vyt]]</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2biv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2biv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2biv RCSB], [http://www.ebi.ac.uk/pdbsum/2biv PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2biv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2biv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2biv RCSB], [http://www.ebi.ac.uk/pdbsum/2biv PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/SCML2_HUMAN SCML2_HUMAN]] Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
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[[Category: Allen, M D.]]
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[[Category: Allen, M D]]
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[[Category: Bycroft, M.]]
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[[Category: Bycroft, M]]
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[[Category: Sait, F.]]
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[[Category: Sait, F]]
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[[Category: Santiveri, C M.]]
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[[Category: Santiveri, C M]]
[[Category: Malignant brain tumor]]
[[Category: Malignant brain tumor]]
[[Category: Transcription]]
[[Category: Transcription]]
[[Category: Transcription factor]]
[[Category: Transcription factor]]

Revision as of 14:54, 24 December 2014

Crystal structure of the wild-type MBT domains of Human SCML2

2biv, resolution 1.70Å

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