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3w86
From Proteopedia
(Difference between revisions)
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| - | + | ==Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with SH-1-96== | |
| - | + | <StructureSection load='3w86' size='340' side='right' caption='[[3w86]], [[Resolution|resolution]] 1.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | ==Function== | + | <table><tr><td colspan='2'>[[3w86]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trycc Trycc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W86 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3W86 FirstGlance]. <br> |
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene>, <scene name='pdbligand=W86:5-{4-[4-(METHOXYCARBONYL)PHENYL]BUTYL}-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC+ACID'>W86</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3w1a|3w1a]], [[3w1l|3w1l]], [[3w1m|3w1m]], [[3w1n|3w1n]], [[3w1p|3w1p]], [[3w1q|3w1q]], [[3w1r|3w1r]], [[3w1t|3w1t]], [[3w1u|3w1u]], [[3w1x|3w1x]], [[3w22|3w22]], [[3w23|3w23]], [[3w2j|3w2j]], [[3w2k|3w2k]], [[3w2l|3w2l]], [[3w2m|3w2m]], [[3w2n|3w2n]], [[3w2u|3w2u]], [[4jd4|4jd4]], [[4jdb|4jdb]], [[3w6y|3w6y]], [[3w70|3w70]], [[3w71|3w71]], [[3w72|3w72]], [[3w73|3w73]], [[3w74|3w74]], [[3w75|3w75]], [[3w76|3w76]], [[3w7c|3w7c]], [[3w7d|3w7d]], [[3w7e|3w7e]], [[3w7g|3w7g]], [[3w7h|3w7h]], [[3w7i|3w7i]], [[3w7j|3w7j]], [[3w7k|3w7k]], [[3w7l|3w7l]], [[3w7m|3w7m]], [[3w7n|3w7n]], [[3w7o|3w7o]], [[3w7p|3w7p]], [[3w7q|3w7q]], [[3w83|3w83]], [[3w84|3w84]], [[3w85|3w85]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PyrD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=353153 TRYCC])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydroorotate_oxidase_(fumarate) Dihydroorotate oxidase (fumarate)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.98.1 1.3.98.1] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w86 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w86 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3w86 RCSB], [http://www.ebi.ac.uk/pdbsum/3w86 PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
[[http://www.uniprot.org/uniprot/PYRD_TRYCC PYRD_TRYCC]] Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor. Molecular oxygen can replace fumarate in vitro. | [[http://www.uniprot.org/uniprot/PYRD_TRYCC PYRD_TRYCC]] Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor. Molecular oxygen can replace fumarate in vitro. | ||
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | [[ | + | [[Category: Trycc]] |
| - | [[Category: Aoki, T | + | [[Category: Aoki, T]] |
| - | [[Category: Balogun, E O | + | [[Category: Balogun, E O]] |
| - | [[Category: Harada, S | + | [[Category: Harada, S]] |
| - | [[Category: Hashimoto, S | + | [[Category: Hashimoto, S]] |
| - | [[Category: Honma, T | + | [[Category: Honma, T]] |
| - | [[Category: Iida, M | + | [[Category: Iida, M]] |
| - | [[Category: Inaoka, D K | + | [[Category: Inaoka, D K]] |
| - | [[Category: Inoue, M | + | [[Category: Inoue, M]] |
| - | [[Category: Kita, K | + | [[Category: Kita, K]] |
| - | [[Category: Kuranaga, T | + | [[Category: Kuranaga, T]] |
| - | [[Category: Lee, N | + | [[Category: Lee, N]] |
| - | [[Category: Matsuoka, S | + | [[Category: Matsuoka, S]] |
| - | [[Category: Montanari, C A | + | [[Category: Montanari, C A]] |
| - | [[Category: Nara, T | + | [[Category: Nara, T]] |
| - | [[Category: Rocha, J R | + | [[Category: Rocha, J R]] |
| - | [[Category: Sakamoto, K | + | [[Category: Sakamoto, K]] |
| - | [[Category: Shiba, T | + | [[Category: Shiba, T]] |
| - | [[Category: Suzuki, S | + | [[Category: Suzuki, S]] |
| - | [[Category: Tabuchi, T | + | [[Category: Tabuchi, T]] |
| - | [[Category: Tanaka, A | + | [[Category: Tanaka, A]] |
[[Category: Cytosol]] | [[Category: Cytosol]] | ||
[[Category: Dihydroorotate/orotate and fumarate/succinate binding]] | [[Category: Dihydroorotate/orotate and fumarate/succinate binding]] | ||
Revision as of 16:18, 24 December 2014
Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with SH-1-96
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Categories: Trycc | Aoki, T | Balogun, E O | Harada, S | Hashimoto, S | Honma, T | Iida, M | Inaoka, D K | Inoue, M | Kita, K | Kuranaga, T | Lee, N | Matsuoka, S | Montanari, C A | Nara, T | Rocha, J R | Sakamoto, K | Shiba, T | Suzuki, S | Tabuchi, T | Tanaka, A | Cytosol | Dihydroorotate/orotate and fumarate/succinate binding | Oxidoreductase | Oxidoreductase-oxidoreductase inhibitor complex | Rossmann fold
