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3wo3

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wo3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wo3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wo3 RCSB], [http://www.ebi.ac.uk/pdbsum/3wo3 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wo3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wo3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wo3 RCSB], [http://www.ebi.ac.uk/pdbsum/3wo3 PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/IL18_HUMAN IL18_HUMAN]] Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. [[http://www.uniprot.org/uniprot/IL18R_HUMAN IL18R_HUMAN]] Receptor for interleukin 18 (IL-18). Binding to the agonist leads to the activation of NF-kappa-B.
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</StructureSection>
</StructureSection>

Revision as of 17:21, 24 December 2014

Crystal structure of IL-18 in complex with IL-18 receptor alpha

3wo3, resolution 3.10Å

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