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2g9p
From Proteopedia
(Difference between revisions)
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g9p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g9p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2g9p RCSB], [http://www.ebi.ac.uk/pdbsum/2g9p PDBsum]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g9p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g9p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2g9p RCSB], [http://www.ebi.ac.uk/pdbsum/2g9p PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/LAT2A_LACTA LAT2A_LACTA]] It has antimicrobial activity against Gram-positive bacteria (A.globiformis VKM Ac-1112 (MIC=0.7 ug/ml), and B.subtilis VKM B-501 (MIC=0.4 ug/ml)), Gram-negative bacteria (E.coli DH5-alpha (MIC=1.0 ug/ml), E.coli MH1 (MIC=0.7 ug/ml), and P.aeruginosa PAO1 (MIC=6.7 ug/ml)), and yeasts (P.pastoris GS115 (MIC=6.7 ug/ml), and S.cerevisiae Y190 (MIC=54 ug/ml)). Also has a strong hemolytic activity against rabbit erythrocytes. Causes paralysis, but is not lethal when injected into insect (Musca domestica) larvae.<ref>PMID:16735513</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Arseniev, A S | + | [[Category: Arseniev, A S]] |
| - | [[Category: Chupin, V V | + | [[Category: Chupin, V V]] |
| - | [[Category: Dubovskii, P V | + | [[Category: Dubovskii, P V]] |
| - | [[Category: Efremov, R G | + | [[Category: Efremov, R G]] |
| - | [[Category: Polyansky, A A | + | [[Category: Polyansky, A A]] |
| - | [[Category: Volynsky, P E | + | [[Category: Volynsky, P E]] |
[[Category: Antimicrobial protein]] | [[Category: Antimicrobial protein]] | ||
[[Category: Helix-hinge-helix]] | [[Category: Helix-hinge-helix]] | ||
Revision as of 19:03, 24 December 2014
NMR structure of a novel antimicrobial peptide, latarcin 2a, from spider (Lachesana tarabaevi) venom
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