4qm1

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qm1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qm1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qm1 RCSB], [http://www.ebi.ac.uk/pdbsum/4qm1 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qm1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qm1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qm1 RCSB], [http://www.ebi.ac.uk/pdbsum/4qm1 PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/Q81W29_BACAN Q81W29_BACAN]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).[HAMAP-Rule:MF_01964]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: IMP dehydrogenase]]
[[Category: IMP dehydrogenase]]
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[[Category: Anderson, W F.]]
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[[Category: Anderson, W F]]
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[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
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[[Category: Structural genomic]]
[[Category: Csgid]]
[[Category: Csgid]]
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[[Category: Gollapalli, D.]]
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[[Category: Gollapalli, D]]
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[[Category: Gorla, S K.]]
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[[Category: Gorla, S K]]
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[[Category: Gu, M.]]
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[[Category: Gu, M]]
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[[Category: Hedstrom, L.]]
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[[Category: Hedstrom, L]]
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[[Category: Joachimiak, A.]]
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[[Category: Joachimiak, A]]
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[[Category: Kim, Y.]]
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[[Category: Kim, Y]]
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[[Category: Makowska-Grzyska, M.]]
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[[Category: Makowska-Grzyska, M]]
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[[Category: Mandapati, K.]]
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[[Category: Mandapati, K]]
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[[Category: Zhang, M.]]
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[[Category: Zhang, M]]
[[Category: Alpha-beta structure]]
[[Category: Alpha-beta structure]]
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[[Category: Center for structural genomics of infectious disease]]
 
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[[Category: Csgid]]
 
[[Category: National institute of allergy and infectious disease]]
[[Category: National institute of allergy and infectious disease]]
[[Category: Niaid]]
[[Category: Niaid]]
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
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[[Category: Structural genomic]]
 
[[Category: Tim barrel]]
[[Category: Tim barrel]]

Revision as of 19:03, 24 December 2014

Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase with an Internal Deletion of the CBS Domain from Bacillus anthracis str. Ames complexed with inhibitor D67

4qm1, resolution 2.80Å

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