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3edr
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3edr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3edr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3edr RCSB], [http://www.ebi.ac.uk/pdbsum/3edr PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3edr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3edr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3edr RCSB], [http://www.ebi.ac.uk/pdbsum/3edr PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CASP7_HUMAN CASP7_HUMAN]] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 19:18, 24 December 2014
The crystal structure of caspase-7 in complex with Acetyl-LDESD-CHO
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