2cto
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cto FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cto OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cto RCSB], [http://www.ebi.ac.uk/pdbsum/2cto PDBsum], [http://www.topsan.org/Proteins/RSGI/2cto TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cto FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cto OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cto RCSB], [http://www.ebi.ac.uk/pdbsum/2cto PDBsum], [http://www.topsan.org/Proteins/RSGI/2cto TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MAEL_HUMAN MAEL_HUMAN]] Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for localization of germ-cell factors to the meiotic nuage (By similarity). | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Inoue, M | + | [[Category: Inoue, M]] |
| - | [[Category: Kamatari, Y O | + | [[Category: Kamatari, Y O]] |
| - | [[Category: Kigawa, T | + | [[Category: Kigawa, T]] |
| - | [[Category: Koshiba, S | + | [[Category: Koshiba, S]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Sato, M | + | [[Category: Sato, M]] |
| - | [[Category: Tomizawa, T | + | [[Category: Tomizawa, T]] |
| - | [[Category: Yokoyama, S | + | [[Category: Yokoyama, S]] |
[[Category: Helix-turn-helix]] | [[Category: Helix-turn-helix]] | ||
[[Category: High mobility group box domain]] | [[Category: High mobility group box domain]] | ||
[[Category: National project on protein structural and functional analyse]] | [[Category: National project on protein structural and functional analyse]] | ||
[[Category: Nppsfa]] | [[Category: Nppsfa]] | ||
| - | [[Category: Riken structural genomics/proteomics initiative]] | ||
[[Category: Rsgi]] | [[Category: Rsgi]] | ||
| - | [[Category: Structural genomic]] | ||
[[Category: Unknown function]] | [[Category: Unknown function]] | ||
Revision as of 19:49, 24 December 2014
Solution structure of the HMG box like domain from human hypothetical protein FLJ14904
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