1zbj
From Proteopedia
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| - | [[Image:1zbj.gif|left|200px]] | + | [[Image:1zbj.gif|left|200px]] |
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| - | '''Inferential Structure Determination of the Fyn SH3 domain using NOESY data from a 15N,H2 enriched protein''' | + | {{Structure |
| + | |PDB= 1zbj |SIZE=350|CAPTION= <scene name='initialview01'>1zbj</scene> | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= [http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2] | ||
| + | |GENE= FYN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
| + | }} | ||
| + | |||
| + | '''Inferential Structure Determination of the Fyn SH3 domain using NOESY data from a 15N,H2 enriched protein''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1ZBJ is a [ | + | 1ZBJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZBJ OCA]. |
==Reference== | ==Reference== | ||
| - | Inferential structure determination., Rieping W, Habeck M, Nilges M, Science. 2005 Jul 8;309(5732):303-6. PMID:[http:// | + | Inferential structure determination., Rieping W, Habeck M, Nilges M, Science. 2005 Jul 8;309(5732):303-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16002620 16002620] |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: transferase]] | [[Category: transferase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:33:30 2008'' |
Revision as of 13:33, 20 March 2008
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| Gene: | FYN (Homo sapiens) | ||||||
| Activity: | Transferase, with EC number and 2.7.10.2 2.7.10.1 and 2.7.10.2 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Inferential Structure Determination of the Fyn SH3 domain using NOESY data from a 15N,H2 enriched protein
Overview
Macromolecular structures calculated from nuclear magnetic resonance data are not fully determined by experimental data but depend on subjective choices in data treatment and parameter settings. This makes it difficult to objectively judge the precision of the structures. We used Bayesian inference to derive a probability distribution that represents the unknown structure and its precision. This probability distribution also determines additional unknowns, such as theory parameters, that previously had to be chosen empirically. We implemented this approach by using Markov chain Monte Carlo techniques. Our method provides an objective figure of merit and improves structural quality.
About this Structure
1ZBJ is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Inferential structure determination., Rieping W, Habeck M, Nilges M, Science. 2005 Jul 8;309(5732):303-6. PMID:16002620
Page seeded by OCA on Thu Mar 20 15:33:30 2008
