2spc
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2spc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2SPC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2SPC FirstGlance]. <br> | <table><tr><td colspan='2'>[[2spc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2SPC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2SPC FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2spc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2spc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2spc RCSB], [http://www.ebi.ac.uk/pdbsum/2spc PDBsum]</span></td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2spc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2spc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2spc RCSB], [http://www.ebi.ac.uk/pdbsum/2spc PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SPTCA_DROME SPTCA_DROME]] Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. Essential for larval survival and development. Stabilizes cell to cell interactions that are critical for the maintenance of cell shape and subcellular organization within embryonic tissues. Lva and spectrin may form a Golgi-based scaffold that mediates interaction of Golgi bodies with microtubules and facilitates Golgi-derived membrane secretion required for the formation of furrows during cellularization.<ref>PMID:8276898</ref> <ref>PMID:3680372</ref> <ref>PMID:11076973</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Drosophila melanogaster]] | [[Category: Drosophila melanogaster]] | ||
| - | [[Category: Branton, D | + | [[Category: Branton, D]] |
| - | [[Category: Cronin, T | + | [[Category: Cronin, T]] |
| - | [[Category: Harrison, S C | + | [[Category: Harrison, S C]] |
| - | [[Category: Viel, A | + | [[Category: Viel, A]] |
| - | [[Category: Winograd, E | + | [[Category: Winograd, E]] |
| - | [[Category: Yan, Y | + | [[Category: Yan, Y]] |
[[Category: Cytoskeleton]] | [[Category: Cytoskeleton]] | ||
Revision as of 20:16, 24 December 2014
CRYSTAL STRUCTURE OF THE REPETITIVE SEGMENTS OF SPECTRIN
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