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1z60

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1z60]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1e53 1e53]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z60 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z60 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1z60]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1e53 1e53]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z60 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z60 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z60 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z60 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z60 RCSB], [http://www.ebi.ac.uk/pdbsum/1z60 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z60 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z60 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1z60 RCSB], [http://www.ebi.ac.uk/pdbsum/1z60 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/TF2H2_HUMAN TF2H2_HUMAN]] Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. The N-terminus interacts with and regulates XPD whereas an intact C-terminus is required for a successful escape of RNAP II form the promoter.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Boelens, R.]]
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[[Category: Boelens, R]]
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[[Category: Dominguez, C.]]
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[[Category: Dominguez, C]]
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[[Category: Fribourg, S.]]
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[[Category: Fribourg, S]]
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[[Category: Kellenberger, E.]]
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[[Category: Kellenberger, E]]
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[[Category: Kieffer, B.]]
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[[Category: Kieffer, B]]
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[[Category: Moras, D.]]
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[[Category: Moras, D]]
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[[Category: Poterszman, A.]]
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[[Category: Poterszman, A]]
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[[Category: Wasielewski, E.]]
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[[Category: Wasielewski, E]]
[[Category: Basic transcription factor]]
[[Category: Basic transcription factor]]
[[Category: Ring finger]]
[[Category: Ring finger]]
[[Category: Transcription]]
[[Category: Transcription]]
[[Category: Zinc binding protein]]
[[Category: Zinc binding protein]]

Revision as of 20:24, 24 December 2014

Solution structure of the carboxy-terminal domain of human TFIIH P44 subunit

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