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4ht1

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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ht1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ht1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ht1 RCSB], [http://www.ebi.ac.uk/pdbsum/4ht1 PDBsum]</span></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ht1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ht1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ht1 RCSB], [http://www.ebi.ac.uk/pdbsum/4ht1 PDBsum]</span></td></tr>
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== Function ==
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[[http://www.uniprot.org/uniprot/TNF12_HUMAN TNF12_HUMAN]] Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines.<ref>PMID:10085077</ref>
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==

Revision as of 20:31, 24 December 2014

Human TWEAK in complex with the Fab fragment of a neutralizing antibody

4ht1, resolution 2.50Å

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