2yeh
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yeh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yeh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yeh RCSB], [http://www.ebi.ac.uk/pdbsum/2yeh PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yeh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yeh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yeh RCSB], [http://www.ebi.ac.uk/pdbsum/2yeh PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/HS90A_HUMAN HS90A_HUMAN]] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:15937123</ref> <ref>PMID:11274138</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Heat Shock Proteins|Heat Shock Proteins]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Baker, L M | + | [[Category: Baker, L M]] |
| - | [[Category: Hubbard, R E | + | [[Category: Hubbard, R E]] |
| - | [[Category: Roughley, S D | + | [[Category: Roughley, S D]] |
[[Category: Chaperone]] | [[Category: Chaperone]] | ||
[[Category: Stress response]] | [[Category: Stress response]] | ||
Revision as of 21:26, 24 December 2014
HSP90 INHIBITORS AND DRUGS FROM FRAGMENT AND VIRTUAL SCREENING
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