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2iap
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2iap]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Loligo_vulgaris Loligo vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IAP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IAP FirstGlance]. <br> | <table><tr><td colspan='2'>[[2iap]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Loligo_vulgaris Loligo vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IAP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IAP FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1e1a|1e1a]], [[1pjx|1pjx]], [[2iao|2iao]], [[2iaq|2iaq]], [[2iar|2iar]], [[2ias|2ias]], [[2iat|2iat]], [[2iau|2iau]], [[2iav|2iav]], [[2iaw|2iaw]], [[2iax|2iax]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1e1a|1e1a]], [[1pjx|1pjx]], [[2iao|2iao]], [[2iaq|2iaq]], [[2iar|2iar]], [[2ias|2ias]], [[2iat|2iat]], [[2iau|2iau]], [[2iav|2iav]], [[2iaw|2iaw]], [[2iax|2iax]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Diisopropyl-fluorophosphatase Diisopropyl-fluorophosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.8.2 3.1.8.2] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Diisopropyl-fluorophosphatase Diisopropyl-fluorophosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.8.2 3.1.8.2] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iap OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2iap RCSB], [http://www.ebi.ac.uk/pdbsum/2iap PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iap OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2iap RCSB], [http://www.ebi.ac.uk/pdbsum/2iap PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DFPA_LOLVU DFPA_LOLVU]] Biological function and substrate unknown. However, it is capable of acting on phosphorus anhydride bonds (such as phosphorus-halide and phosphorus-cyanide) in organophosphorus compounds (including nerve gases).<ref>PMID:15966726</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Diisopropyl-fluorophosphatase]] | [[Category: Diisopropyl-fluorophosphatase]] | ||
[[Category: Loligo vulgaris]] | [[Category: Loligo vulgaris]] | ||
| - | [[Category: Fritzsch, G | + | [[Category: Fritzsch, G]] |
| - | [[Category: Koepke, J | + | [[Category: Koepke, J]] |
| - | [[Category: Luecke, C | + | [[Category: Luecke, C]] |
| - | [[Category: Rueterjans, H | + | [[Category: Rueterjans, H]] |
| - | [[Category: Scharff, E I | + | [[Category: Scharff, E I]] |
[[Category: Beta-propeller]] | [[Category: Beta-propeller]] | ||
[[Category: Calcium-binding site]] | [[Category: Calcium-binding site]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Phosphotriesterase]] | [[Category: Phosphotriesterase]] | ||
Revision as of 21:31, 24 December 2014
Crystal structure of squid ganglion DFPase E21Q mutant
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