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1ii3

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1ii3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1II3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1II3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1ii3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1II3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1II3 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ey0|1ey0]], [[1ihz|1ihz]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ey0|1ey0]], [[1ihz|1ihz]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Micrococcal_nuclease Micrococcal nuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.31.1 3.1.31.1] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Micrococcal_nuclease Micrococcal nuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.31.1 3.1.31.1] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ii3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ii3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ii3 RCSB], [http://www.ebi.ac.uk/pdbsum/1ii3 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ii3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ii3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ii3 RCSB], [http://www.ebi.ac.uk/pdbsum/1ii3 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/NUC_STAAU NUC_STAAU]] Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Micrococcal nuclease]]
[[Category: Micrococcal nuclease]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
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[[Category: Chen, J.]]
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[[Category: Chen, J]]
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[[Category: Lu, Z.]]
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[[Category: Lu, Z]]
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[[Category: Sakon, J.]]
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[[Category: Sakon, J]]
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[[Category: Stites, W E.]]
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[[Category: Stites, W E]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]

Revision as of 21:56, 24 December 2014

Structure of S. nuclease quintuple mutant V23I/V66L/I72L/I92L/V99L

1ii3, resolution 1.72Å

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