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1kt1

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1kt1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saimiri_boliviensis Saimiri boliviensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KT1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KT1 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1kt1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saimiri_boliviensis Saimiri boliviensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KT1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KT1 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1kt0|1kt0]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1kt0|1kt0]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kt1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kt1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1kt1 RCSB], [http://www.ebi.ac.uk/pdbsum/1kt1 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kt1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kt1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1kt1 RCSB], [http://www.ebi.ac.uk/pdbsum/1kt1 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/FKBP5_SAIBB FKBP5_SAIBB]] Interacts with functionally mature heterooligomeric progesterone receptor complexes along with HSP90 and TEBP (By similarity). Interacts with the glucocorticoid receptor and modulates its response to glucocorticoids.<ref>PMID:11089542</ref> <ref>PMID:12538866</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Peptidylprolyl isomerase]]
[[Category: Peptidylprolyl isomerase]]
[[Category: Saimiri boliviensis]]
[[Category: Saimiri boliviensis]]
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[[Category: Cheung-Flynn, J.]]
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[[Category: Cheung-Flynn, J]]
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[[Category: Clardy, J C.]]
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[[Category: Clardy, J C]]
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[[Category: Rimerman, R A.]]
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[[Category: Rimerman, R A]]
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[[Category: Scammell, J G.]]
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[[Category: Scammell, J G]]
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[[Category: Sinars, C R.]]
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[[Category: Sinars, C R]]
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[[Category: Smith, D F.]]
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[[Category: Smith, D F]]
[[Category: Fkbp-like ppiase]]
[[Category: Fkbp-like ppiase]]
[[Category: Isomerase]]
[[Category: Isomerase]]
[[Category: Tpr repeat]]
[[Category: Tpr repeat]]

Revision as of 23:34, 24 December 2014

Structure of the Large FKBP-like Protein, FKBP51, Involved in Steroid Receptor Complexes

1kt1, resolution 2.80Å

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