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2aoz
From Proteopedia
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| - | [[Image:2aoz.gif|left|200px]] | + | [[Image:2aoz.gif|left|200px]] |
| - | + | ||
| - | '''Crystal structure of the myotoxin-II from Atropoides nummifer venom''' | + | {{Structure |
| + | |PDB= 2aoz |SIZE=350|CAPTION= <scene name='initialview01'>2aoz</scene>, resolution 2.08Å | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=SO4:SULFATE ION'>SO4</scene> | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''Crystal structure of the myotoxin-II from Atropoides nummifer venom''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 2AOZ is a [ | + | 2AOZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Atropoides_nummifer Atropoides nummifer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AOZ OCA]. |
==Reference== | ==Reference== | ||
| - | Structure of myotoxin II, a catalytically inactive Lys49 phospholipase A2 homologue from Atropoides nummifer venom., Murakami MT, Melo CC, Angulo Y, Lomonte B, Arni RK, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 May 1;62(Pt, 5):423-6. Epub 2006 Apr 12. PMID:[http:// | + | Structure of myotoxin II, a catalytically inactive Lys49 phospholipase A2 homologue from Atropoides nummifer venom., Murakami MT, Melo CC, Angulo Y, Lomonte B, Arni RK, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 May 1;62(Pt, 5):423-6. Epub 2006 Apr 12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16682766 16682766] |
[[Category: Atropoides nummifer]] | [[Category: Atropoides nummifer]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: x-ray diffration]] | [[Category: x-ray diffration]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:52:08 2008'' |
Revision as of 13:52, 20 March 2008
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| , resolution 2.08Å | |||||||
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| Ligands: | |||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of the myotoxin-II from Atropoides nummifer venom
Overview
Lys49 snake-venom phospholipase A2 (PLA2) homologues are highly myotoxic proteins which, although lacking catalytic activity, possess the ability to disrupt biological membranes, inducing significant muscle-tissue loss and permanent disability in severely envenomed patients. Since the structural basis for their toxic activity is still only partially understood, the structure of myotoxin II, a monomeric Lys49 PLA2 homologue from Atropoides nummifer, has been determined at 2.08 angstroms resolution and the anion-binding site has been characterized.
About this Structure
2AOZ is a Single protein structure of sequence from Atropoides nummifer. Full crystallographic information is available from OCA.
Reference
Structure of myotoxin II, a catalytically inactive Lys49 phospholipase A2 homologue from Atropoides nummifer venom., Murakami MT, Melo CC, Angulo Y, Lomonte B, Arni RK, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 May 1;62(Pt, 5):423-6. Epub 2006 Apr 12. PMID:16682766
Page seeded by OCA on Thu Mar 20 15:52:08 2008
