This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1lki
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1lki]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LKI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1LKI FirstGlance]. <br> | <table><tr><td colspan='2'>[[1lki]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LKI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1LKI FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1lki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lki OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1lki RCSB], [http://www.ebi.ac.uk/pdbsum/1lki PDBsum]</span></td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1lki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lki OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1lki RCSB], [http://www.ebi.ac.uk/pdbsum/1lki PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/LIF_MOUSE LIF_MOUSE]] LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 28: | Line 30: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Grey, L M | + | [[Category: Grey, L M]] |
| - | [[Category: Heath, J K | + | [[Category: Heath, J K]] |
| - | [[Category: Jones, E Y | + | [[Category: Jones, E Y]] |
| - | [[Category: Robinson, R C | + | [[Category: Robinson, R C]] |
| - | [[Category: Staunton, D | + | [[Category: Staunton, D]] |
| - | [[Category: Stuart, D I | + | [[Category: Stuart, D I]] |
[[Category: Cytokine]] | [[Category: Cytokine]] | ||
[[Category: Four helix bundle]] | [[Category: Four helix bundle]] | ||
Revision as of 01:23, 25 December 2014
THE CRYSTAL STRUCTURE AND BIOLOGICAL FUNCTION OF LEUKEMIA INHIBITORY FACTOR: IMPLICATIONS FOR RECEPTOR BINDING
| |||||||||||
