This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2oxc
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2oxc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OXC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OXC FirstGlance]. <br> | <table><tr><td colspan='2'>[[2oxc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OXC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OXC FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DDX20, DP103, GEMIN3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DDX20, DP103, GEMIN3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2oxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oxc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2oxc RCSB], [http://www.ebi.ac.uk/pdbsum/2oxc PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2oxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oxc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2oxc RCSB], [http://www.ebi.ac.uk/pdbsum/2oxc PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DDX20_HUMAN DDX20_HUMAN]] The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 21: | Line 23: | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Arrowsmith, C H]] | [[Category: Arrowsmith, C H]] | ||
| - | [[Category: Berg, S Van Den | + | [[Category: Berg, S Van Den]] |
| - | [[Category: Berglund, H | + | [[Category: Berglund, H]] |
| - | [[Category: Busam, R D | + | [[Category: Busam, R D]] |
| - | [[Category: Collins, R | + | [[Category: Collins, R]] |
| - | [[Category: Dahlgren, L G | + | [[Category: Dahlgren, L G]] |
| - | [[Category: Edwards, A | + | [[Category: Edwards, A]] |
| - | [[Category: Flodin, S | + | [[Category: Flodin, S]] |
| - | [[Category: Flores, A | + | [[Category: Flores, A]] |
| - | [[Category: Graslund, S | + | [[Category: Graslund, S]] |
| - | [[Category: Hallberg, B M | + | [[Category: Hallberg, B M]] |
| - | [[Category: Hammarstrom, M | + | [[Category: Hammarstrom, M]] |
| - | [[Category: Hogbom, M | + | [[Category: Hogbom, M]] |
| - | [[Category: Holmberg-Schiavone, L | + | [[Category: Holmberg-Schiavone, L]] |
| - | [[Category: Johansson, I | + | [[Category: Johansson, I]] |
| - | [[Category: Karlberg, T | + | [[Category: Karlberg, T]] |
| - | [[Category: Kotenyova, T | + | [[Category: Kotenyova, T]] |
| - | [[Category: Lehtio, L | + | [[Category: Lehtio, L]] |
| - | [[Category: Moche, M | + | [[Category: Moche, M]] |
| - | [[Category: Nordlund, P | + | [[Category: Nordlund, P]] |
| - | [[Category: Nyman, T | + | [[Category: Nyman, T]] |
| - | [[Category: Ogg, D | + | [[Category: Ogg, D]] |
| - | [[Category: Persson, C | + | [[Category: Persson, C]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Sagemark, J | + | [[Category: Sagemark, J]] |
| - | [[Category: Stenmark, P | + | [[Category: Stenmark, P]] |
| - | [[Category: Sundstrom, M | + | [[Category: Sundstrom, M]] |
| - | [[Category: Thorsell, A G | + | [[Category: Thorsell, A G]] |
| - | [[Category: Weigelt, J | + | [[Category: Weigelt, J]] |
[[Category: Dead]] | [[Category: Dead]] | ||
[[Category: Helicase]] | [[Category: Helicase]] | ||
| Line 54: | Line 56: | ||
[[Category: Rna]] | [[Category: Rna]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
| - | [[Category: Structural genomic]] | ||
| - | [[Category: Structural genomics consortium]] | ||
Revision as of 01:34, 25 December 2014
Human DEAD-box RNA helicase DDX20, DEAD domain in complex with ADP
| |||||||||||
Categories: Homo sapiens | Arrowsmith, C H | Berg, S Van Den | Berglund, H | Busam, R D | Collins, R | Dahlgren, L G | Edwards, A | Flodin, S | Flores, A | Graslund, S | Hallberg, B M | Hammarstrom, M | Hogbom, M | Holmberg-Schiavone, L | Johansson, I | Karlberg, T | Kotenyova, T | Lehtio, L | Moche, M | Nordlund, P | Nyman, T | Ogg, D | Persson, C | Structural genomic | Sagemark, J | Stenmark, P | Sundstrom, M | Thorsell, A G | Weigelt, J | Dead | Helicase | Hydrolase | Rna | Sgc
