2awb

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[[Image:2awb.gif|left|200px]]<br /><applet load="2awb" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:2awb.gif|left|200px]]
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caption="2awb, resolution 3.46&Aring;" />
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'''Crystal structure of the bacterial ribosome from Escherichia coli at 3.5 A resolution. This file contains the 50S subunit of the second 70S ribosome. The entire crystal structure contains two 70S ribosomes and is described in remark 400.'''<br />
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{{Structure
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|PDB= 2awb |SIZE=350|CAPTION= <scene name='initialview01'>2awb</scene>, resolution 3.46&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=MG:MAGNESIUM ION'>MG</scene>
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|ACTIVITY=
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|GENE=
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}}
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'''Crystal structure of the bacterial ribosome from Escherichia coli at 3.5 A resolution. This file contains the 50S subunit of the second 70S ribosome. The entire crystal structure contains two 70S ribosomes and is described in remark 400.'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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2AWB is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=MG:'>MG</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AWB OCA].
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2AWB is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AWB OCA].
==Reference==
==Reference==
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Structures of the bacterial ribosome at 3.5 A resolution., Schuwirth BS, Borovinskaya MA, Hau CW, Zhang W, Vila-Sanjurjo A, Holton JM, Cate JH, Science. 2005 Nov 4;310(5749):827-34. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16272117 16272117]
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Structures of the bacterial ribosome at 3.5 A resolution., Schuwirth BS, Borovinskaya MA, Hau CW, Zhang W, Vila-Sanjurjo A, Holton JM, Cate JH, Science. 2005 Nov 4;310(5749):827-34. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16272117 16272117]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: rna-protein complex]]
[[Category: rna-protein complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:31:36 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:54:34 2008''

Revision as of 13:54, 20 March 2008


PDB ID 2awb

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, resolution 3.46Å
Ligands:
Coordinates: save as pdb, mmCIF, xml



Crystal structure of the bacterial ribosome from Escherichia coli at 3.5 A resolution. This file contains the 50S subunit of the second 70S ribosome. The entire crystal structure contains two 70S ribosomes and is described in remark 400.


Overview

We describe two structures of the intact bacterial ribosome from Escherichia coli determined to a resolution of 3.5 angstroms by x-ray crystallography. These structures provide a detailed view of the interface between the small and large ribosomal subunits and the conformation of the peptidyl transferase center in the context of the intact ribosome. Differences between the two ribosomes reveal a high degree of flexibility between the head and the rest of the small subunit. Swiveling of the head of the small subunit observed in the present structures, coupled to the ratchet-like motion of the two subunits observed previously, suggests a mechanism for the final movements of messenger RNA (mRNA) and transfer RNAs (tRNAs) during translocation.

About this Structure

2AWB is a Protein complex structure of sequences from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Structures of the bacterial ribosome at 3.5 A resolution., Schuwirth BS, Borovinskaya MA, Hau CW, Zhang W, Vila-Sanjurjo A, Holton JM, Cate JH, Science. 2005 Nov 4;310(5749):827-34. PMID:16272117

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