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3wcn
From Proteopedia
(Difference between revisions)
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<StructureSection load='3wcn' size='340' side='right' caption='[[3wcn]], [[Resolution|resolution]] 3.35Å' scene=''> | <StructureSection load='3wcn' size='340' side='right' caption='[[3wcn]], [[Resolution|resolution]] 3.35Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3wcn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aquae Aquae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WCN OCA]. <br> | + | <table><tr><td colspan='2'>[[3wcn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aquae Aquae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WCN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WCN FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=THJ:THIOSULFATE'>THJ</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=THJ:THIOSULFATE'>THJ</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3w1h|3w1h]], [[3w1i|3w1i]], [[3w1j|3w1j]], [[3w1k|3w1k]], [[3wco|3wco]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3w1h|3w1h]], [[3w1i|3w1i]], [[3w1j|3w1j]], [[3w1k|3w1k]], [[3wco|3wco]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aq_1031, selA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224324 AQUAE])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aq_1031, selA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224324 AQUAE])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-seryl-tRNA(Sec)_selenium_transferase L-seryl-tRNA(Sec) selenium transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.9.1.1 2.9.1.1] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wcn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wcn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wcn RCSB], [http://www.ebi.ac.uk/pdbsum/3wcn PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wcn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wcn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wcn RCSB], [http://www.ebi.ac.uk/pdbsum/3wcn PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SELA_AQUAE SELA_AQUAE]] Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Dimer-Dimer Interaction of the Bacterial Selenocysteine Synthase SelA Promotes Functional Active-Site Formation and Catalytic Specificity.,Itoh Y, Brocker MJ, Sekine SI, Soll D, Yokoyama S J Mol Biol. 2014 Jan 20. pii: S0022-2836(14)00022-9. doi:, 10.1016/j.jmb.2014.01.003. PMID:24456689<ref>PMID:24456689</ref> | Dimer-Dimer Interaction of the Bacterial Selenocysteine Synthase SelA Promotes Functional Active-Site Formation and Catalytic Specificity.,Itoh Y, Brocker MJ, Sekine SI, Soll D, Yokoyama S J Mol Biol. 2014 Jan 20. pii: S0022-2836(14)00022-9. doi:, 10.1016/j.jmb.2014.01.003. PMID:24456689<ref>PMID:24456689</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Selenocysteine synthase|Selenocysteine synthase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Aquae]] | [[Category: Aquae]] | ||
| - | [[Category: Itoh, Y | + | [[Category: Itoh, Y]] |
| - | [[Category: Sekine, S | + | [[Category: Sekine, S]] |
| - | [[Category: Yokoyama, S | + | [[Category: Yokoyama, S]] |
[[Category: Selenium metabolism]] | [[Category: Selenium metabolism]] | ||
[[Category: Selenocysteine synthesis]] | [[Category: Selenocysteine synthesis]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 02:18, 25 December 2014
Crystal structure of the depentamerized mutant of selenocysteine synthase SelA
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