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3k84

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k84 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3k84 RCSB], [http://www.ebi.ac.uk/pdbsum/3k84 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k84 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3k84 RCSB], [http://www.ebi.ac.uk/pdbsum/3k84 PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/FAAH1_RAT FAAH1_RAT]] Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 02:34, 25 December 2014

Crystal Structure Analysis of a Oleyl/Oxadiazole/pyridine Inhibitor Bound to a Humanized Variant of Fatty Acid Amide Hydrolase

3k84, resolution 2.25Å

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