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3u00
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3u00]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rana_pipiens Rana pipiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U00 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3U00 FirstGlance]. <br> | <table><tr><td colspan='2'>[[3u00]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rana_pipiens Rana pipiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U00 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3U00 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr> | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3phn|3phn]], [[3hg6|3hg6]], [[1onc|1onc]], [[3u01|3u01]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3phn|3phn]], [[3hg6|3hg6]], [[1onc|1onc]], [[3u01|3u01]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u00 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u00 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u00 RCSB], [http://www.ebi.ac.uk/pdbsum/3u00 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u00 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u00 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u00 RCSB], [http://www.ebi.ac.uk/pdbsum/3u00 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/RNP30_RANPI RNP30_RANPI]] Basic protein with antiproliferative/cytotoxic activity against several tumor cell lines in vitro, as well as antitumor in vivo. It exhibits a ribonuclease-like activity against high molecular weight ribosomal RNA. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Rana pipiens]] | [[Category: Rana pipiens]] | ||
| - | [[Category: Kurpiewska, K | + | [[Category: Kurpiewska, K]] |
| - | [[Category: Lewinski, K | + | [[Category: Lewinski, K]] |
| - | [[Category: Loch, J | + | [[Category: Loch, J]] |
| - | [[Category: Ribo, M | + | [[Category: Ribo, M]] |
| - | [[Category: Torrent, G | + | [[Category: Torrent, G]] |
| - | [[Category: Vilanova, M | + | [[Category: Vilanova, M]] |
[[Category: Alpha/beta protein]] | [[Category: Alpha/beta protein]] | ||
[[Category: Antitumor protein]] | [[Category: Antitumor protein]] | ||
Revision as of 02:37, 25 December 2014
Crystal structure of wild-type onconase at 1.65 A resolution
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