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4wh7
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wh7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wh7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wh7 RCSB], [http://www.ebi.ac.uk/pdbsum/4wh7 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wh7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wh7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wh7 RCSB], [http://www.ebi.ac.uk/pdbsum/4wh7 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MPIP2_HUMAN MPIP2_HUMAN]] Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity.<ref>PMID:17332740</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 03:01, 25 December 2014
Structure of the CDC25B Phosphatase Catalytic Domain with Bound Ligand
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