1vcs
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1vcs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VCS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VCS FirstGlance]. <br> | <table><tr><td colspan='2'>[[1vcs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VCS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VCS FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Mus musculus adult male lung cDNA, RIKEN full-length enriched library, clone:1200014A22 product: Vti1a (amino acid 6-94) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Mus musculus adult male lung cDNA, RIKEN full-length enriched library, clone:1200014A22 product: Vti1a (amino acid 6-94) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vcs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vcs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1vcs RCSB], [http://www.ebi.ac.uk/pdbsum/1vcs PDBsum], [http://www.topsan.org/Proteins/RSGI/1vcs TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vcs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vcs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1vcs RCSB], [http://www.ebi.ac.uk/pdbsum/1vcs PDBsum], [http://www.topsan.org/Proteins/RSGI/1vcs TOPSAN]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/VTI1A_MOUSE VTI1A_MOUSE]] V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non-conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2. May be concerned with increased secretion of cytokines associated with cellular senescence.<ref>PMID:19138172</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Abe, T | + | [[Category: Abe, T]] |
| - | [[Category: Hirota, H | + | [[Category: Hirota, H]] |
| - | [[Category: Kigawa, T | + | [[Category: Kigawa, T]] |
| - | [[Category: Koshiba, S | + | [[Category: Koshiba, S]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Tomizawa, T | + | [[Category: Tomizawa, T]] |
| - | [[Category: Yokoyama, S | + | [[Category: Yokoyama, S]] |
[[Category: Habc domain]] | [[Category: Habc domain]] | ||
[[Category: Left-handed twist]] | [[Category: Left-handed twist]] | ||
[[Category: Membrane fusion]] | [[Category: Membrane fusion]] | ||
| - | [[Category: Riken structural genomics/proteomics initiative]] | ||
[[Category: Rsgi]] | [[Category: Rsgi]] | ||
[[Category: Snare]] | [[Category: Snare]] | ||
| - | [[Category: Structural genomic]] | ||
[[Category: Unknown function]] | [[Category: Unknown function]] | ||
[[Category: Up and down three helix bundle]] | [[Category: Up and down three helix bundle]] | ||
[[Category: Vesicle transport]] | [[Category: Vesicle transport]] | ||
[[Category: Vti1]] | [[Category: Vti1]] | ||
Revision as of 03:37, 25 December 2014
Solution Structure of RSGI RUH-009, an N-Terminal Domain of Vti1a [Mus musculus]
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