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1mzr
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1mzr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MZR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MZR FirstGlance]. <br> | <table><tr><td colspan='2'>[[1mzr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MZR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MZR FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">yqhe ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">yqhe ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mzr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mzr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1mzr RCSB], [http://www.ebi.ac.uk/pdbsum/1mzr PDBsum], [http://www.topsan.org/Proteins/BIGS/1mzr TOPSAN]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mzr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mzr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1mzr RCSB], [http://www.ebi.ac.uk/pdbsum/1mzr PDBsum], [http://www.topsan.org/Proteins/BIGS/1mzr TOPSAN]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DKGA_ECOLI DKGA_ECOLI]] Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). It is also capable of stereoselective -keto ester reductions on ethyl acetoacetate and other 2-substituted derivatives. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: Abergel, C | + | [[Category: Abergel, C]] |
| - | [[Category: Claverie, J M | + | [[Category: Claverie, J M]] |
| - | [[Category: IGS-CNRS, France BIGSBacterial targets at | + | [[Category: IGS-CNRS, France BIGSBacterial targets at]] |
| - | [[Category: Jeudy, S | + | [[Category: Jeudy, S]] |
| - | [[Category: Monchois, V | + | [[Category: Monchois, V]] |
[[Category: Aldo-ketoreductase]] | [[Category: Aldo-ketoreductase]] | ||
[[Category: Alpha/beta-barrel]] | [[Category: Alpha/beta-barrel]] | ||
Revision as of 03:38, 25 December 2014
Structure of dkga from E.coli at 2.13 A resolution solved by molecular replacement
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