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1sbx

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1sbx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SBX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SBX FirstGlance]. <br>
<table><tr><td colspan='2'>[[1sbx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SBX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SBX FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SKI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SKI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sbx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sbx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1sbx RCSB], [http://www.ebi.ac.uk/pdbsum/1sbx PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sbx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sbx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1sbx RCSB], [http://www.ebi.ac.uk/pdbsum/1sbx PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/SKI_HUMAN SKI_HUMAN]] May play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage. Functions as a repressor of TGF-beta signaling.<ref>PMID:19049980</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Hegde, R S.]]
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[[Category: Hegde, R S]]
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[[Category: Joachimiak, A.]]
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[[Category: Joachimiak, A]]
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[[Category: Malakhova, M.]]
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[[Category: Malakhova, M]]
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[[Category: Wilson, J J.]]
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[[Category: Wilson, J J]]
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[[Category: Zhang, R.]]
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[[Category: Zhang, R]]
[[Category: Forkhead]]
[[Category: Forkhead]]
[[Category: Oncoprotein]]
[[Category: Oncoprotein]]
[[Category: Winged helix]]
[[Category: Winged helix]]

Revision as of 04:16, 25 December 2014

Crystal structure of the Dachshund-homology domain of human SKI

1sbx, resolution 1.65Å

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