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1di1
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1di1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1di1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1di1 RCSB], [http://www.ebi.ac.uk/pdbsum/1di1 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1di1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1di1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1di1 RCSB], [http://www.ebi.ac.uk/pdbsum/1di1 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ARIS_PENRO ARIS_PENRO]] Catalyzes the cyclization of trans,trans-farnesyl diphosphate (FPP) to the bicyclic sesquiterpene aristolochene. Produces germacrene A as an enzyme-bound intermediate that is not released by the enzyme, but is further cyclized to produce aristolochene. Aristolochene is the likely parent compound for a number of sesquiterpenoid toxins produced by filamentous fungi.<ref>PMID:8440737</ref> <ref>PMID:15186158</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 05:42, 25 December 2014
CRYSTAL STRUCTURE OF ARISTOLOCHENE SYNTHASE FROM PENICILLIUM ROQUEFORTI
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