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3f5c

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3f5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f5c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3f5c RCSB], [http://www.ebi.ac.uk/pdbsum/3f5c PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3f5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f5c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3f5c RCSB], [http://www.ebi.ac.uk/pdbsum/3f5c PDBsum]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/NR5A2_MOUSE NR5A2_MOUSE]] Binds to promoters containing the sequence element 5'-AACGACCGACCTTGAG-3'. Plays a role in the regulation of gene expression in liver and pancreas. May play a role in embryonic development (By similarity). [[http://www.uniprot.org/uniprot/NR0B1_MOUSE NR0B1_MOUSE]] Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity).<ref>PMID:16466956</ref>
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==

Revision as of 06:58, 25 December 2014

Structure of Dax-1:LRH-1 complex

3f5c, resolution 3.00Å

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