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3d8b
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3d8b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d8b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3d8b RCSB], [http://www.ebi.ac.uk/pdbsum/3d8b PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3d8b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d8b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3d8b RCSB], [http://www.ebi.ac.uk/pdbsum/3d8b PDBsum]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/FIGL1_HUMAN FIGL1_HUMAN]] Involved in DNA double-strand break (DBS) repair via homologous recombination (HR). Recruited at DSB sites independently of BRCA2, RAD51 and RAD51 paralogs in a H2AX-dependent manner. May regulate osteoblast proliferation and differentiation.<ref>PMID:23754376</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 07:17, 25 December 2014
Crystal structure of human fidgetin-like protein 1 in complex with ADP
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Categories: Homo sapiens | Andersson, J | Arrowsmith, C H | Berg, S Van Den | Berglund, H | Busam, R D | Collins, R | Dahlgren, L G | Edwards, A M | Flodin, S | Flores, A | Graslund, S | Hammarstrom, M | Johansson, A | Johansson, I | Kallas, A | Karlberg, T | Kotenyova, T | Lehtio, L | Moche, M | Nilsson, M E | Nordlund, P | Nyman, T | Olesen, K | Persson, C | Structural genomic | Sagemark, J | Schuler, H | Thorsell, A G | Tresaugues, L | Welin, M | Wikstrom, M | Wisniewska, M | Aaa+ | Adp | Atp-binding | Atpase | Hydrolase | Magnesium | Metal-binding | Nucleotide-binding | Phosphoprotein | Sgc
